Islington-Six Points, known officially as Islington-City Centre West is the historic central commercial neighbourhood of the former City of Etobicoke. 

The eastern half of this area, where Dundas Street (the first highway connecting Toronto to the West) crosses the Mimico Creek, was originally known as Mimico. It was centred around Montgomery's Inn which was built in 1832.With the building of the first railway to Toronto in 1855, Mimico-on- the-Lake petitioned the government for a post office to be called Mimico in 1858. In 1860 northern Mimico petitioned for its own post office to be named Islington, a name suggested by the wife of Montgomery's Innkeeper who was born in the english city of the same name.Etobicoke was officially incorporated as a township in 1850 first using Montgomery's Inn for its meetings until the former Methodist Church on Dundas at the Mimico Creek was aquired.

Islington-Six Points is a very diverse part of the city. It is dominated by Highway 427 and the QEW/Gardiner Expressway, as well as the railyards of the CPR. Along the highways are a mix of shopping malls and light industrial buildings. There is a mix of single family homes in the south western area with numerous apartment towers along Bloor Street. The area north of the Bloor-Dundas intersection is also known as "Six Points". The Six Points area is a mix of single family bungalows and commercial storefronts along the main streets.